Fatigue, Tachycardia
Conditions
Keywords
heart rate, blood pressure, caffeine, energy drink
Brief summary
* The primary objective of this study is to assess the effect of an energy drink on ventricular repolarization as measured by the interval between the cardiac Q wave and the cardiac T wave (QT interval)obtained from the body surface ECG. * The secondary objective is to assess the effects of an energy drink on heart rate and blood pressure (hemodynamic effects). To place the observed changes in context, comparison will be made to a commonly consumed drink, coffee: Starbuck's K-cup Breakfast Blend.
Detailed description
This study will assess cardiac repolarization before and after three conditions each of which will involve the subject drinking beverages of varying caffeine content.
Interventions
DIETARY_SUPPLEMENTMonster Energy Drink
Small Dose of Monster energy drink. This will be given at a dose of 2mg caffeine/kg body weight (equivalent to approximately one 16 ounce can of monster energy drink for a person weighing 75 kg).
DIETARY_SUPPLEMENTMonster energy drink
Medium Dose of Monster Energy Drink. This will be given at a dose of 3 mg caffeine/kg body weight (equivalent to approximately one 24 ounce can of monster energy drink for a person weighing 75 kg).
DIETARY_SUPPLEMENTCoffee
Coffee. This will be given at a dose of 2mg caffeine/kg body weight (equivalent to approximately one 8 ounce cup of coffee drink for a person weighing 75 kg).
Sponsors
University of Texas at Austin
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy * BMI between 24 - 29
Exclusion criteria
* Resting heart rate below 60 bpm * Resting heart rate above 88 bpm * Cardiovascular or metabolic disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| QT interval will be measured in msec | 19 hrs | The investigators will be measuring cardiac QT interval before (baseline) and for 5 hours post beverage consumption. The measurements will be made in msec. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate will be measured as beats per minute. | 19 hrs | The investigators will be measuring cardiac heart rate before (baseline) and for 5 hours post beverage consumption. The measurements will be made as beats per minute. |
| Blood Pressure will be measured in the brachial artery as mmHG | 19 hrs | The investigators will be measuring artery blood pressure before (baseline) and for 5 hours post beverage consumption. The measurements will be made as mmHg. |
Countries
United States
Outcome results
None listed