Pancreatic Endocrine Neoplasms
Conditions
Keywords
Endocrine Pancreas, Pancreatic Endocrine Neoplasm
Brief summary
A single institutional study of Pancreatic Endocrine Neoplasms over 18 years.
Detailed description
The investigators did an analysis from a prospectively maintained database of patients who underwent pancreatic resections or nonresective procedures for neoplasms of the pancreas at Sir Ganga Ram Hospital from 1995 to 2013 and using pathological reports and preoperative CT scan as the gold standard, the investigators identified 40 patients with PENs.
Interventions
None listed
Sponsors
Sir Ganga Ram Hospital
Medical College and Hospital Kolkata
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Pathological reports and Prooperative CAT Scan showing Endocrine Pancreatic Tumours
Exclusion criteria
* Nonendocrine Pancreatic Tumours
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nonfunctioning and Malignant Pancreatic Endocrine Neoplasms | Each participant was followed up for a period of 5 years | Of the 40 patients operated for Pancreatic Endocrine Neoplasms, using clinical criteria, histopathological analysis and preoperative imaging as gold standard, nonfunctioning and functioning tumours were identified. Similarly the number of benign and malignant lesions identified were recorded as per the WHO Classification of pancreatic endocrine tumours. |
Participant flow
Recruitment details
An analysis from a prospectively maintained database of patients was done who underwent pancreatic surgery for neoplasms of the pancreas at Sir Ganga Ram Hospital, New Delhi, India from 1995 to 2013 and using pathological reports and preoperative CT scan as gold standard, we identified 40 patients with PENs
Participants by arm
| Arm | Count |
|---|---|
| Patients Operated for Pancreatic Endocrine Neoplasms We did an observational analysis from a prospectively maintained database of patients who underwent pancreatic surgery for neoplasms of the pancreas at Sir Ganga Ram Hospital, New Delhi, India from 1995 to 2013 and using pathological reports and preoperative CT scan as gold standard, we identified 40 patients with PENs. | 40 |
| Total | 40 |
Baseline characteristics
| Characteristic | Patients Operated for Pancreatic Endocrine Neoplasms |
|---|---|
| Age, Continuous | 48.6 years STANDARD_DEVIATION 15.52 |
| Region of Enrollment India | 40 participants |
| Sex: Female, Male Female | 18 Participants |
| Sex: Female, Male Male | 22 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 16 / 40 |
| serious Total, serious adverse events | 6 / 40 |
Outcome results
Primary
Nonfunctioning and Malignant Pancreatic Endocrine Neoplasms
Of the 40 patients operated for Pancreatic Endocrine Neoplasms, using clinical criteria, histopathological analysis and preoperative imaging as gold standard, nonfunctioning and functioning tumours were identified. Similarly the number of benign and malignant lesions identified were recorded as per the WHO Classification of pancreatic endocrine tumours.
Time frame: Each participant was followed up for a period of 5 years
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Patients Operated for Pancreatic Endocrine Neoplasms | Nonfunctioning and Malignant Pancreatic Endocrine Neoplasms | Nonfunctioning Tumours | 28 participants |
| Patients Operated for Pancreatic Endocrine Neoplasms | Nonfunctioning and Malignant Pancreatic Endocrine Neoplasms | Functioning Tumours | 12 participants |
| Patients Operated for Pancreatic Endocrine Neoplasms | Nonfunctioning and Malignant Pancreatic Endocrine Neoplasms | Benign Tumours | 22 participants |
| Patients Operated for Pancreatic Endocrine Neoplasms | Nonfunctioning and Malignant Pancreatic Endocrine Neoplasms | Malignant Tumours | 18 participants |