Ultrasound TFP (Transversalis Fascia Plane) for Analgesia After Iliac Crest Bone Graft Harvest

Intérêt du TFP (Transversalis Fascia Plane) Bloc échoguidé Pour l'analgésie du prélèvement Osseux de crête Iliaque

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02398474

Acronym

TFP

Enrollment

Registered

2015-03-25

Start date

2015-05-12

Completion date

2018-12-31

Last updated

2019-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Scheduled for Iliac Crest Bone Graft Harvest During Upper or Lower Limb Surgery

Brief summary

Iliac crest bone graft harvest is associated with acute pain that can lead to chronic postoperative pain. Local anesthetic infiltration and regional anesthesia could be of interest to reduce opioid consumption during and after surgery, reduce hyperalgesia and the associated risk of chronic postoperative pain. In this surgery, local anesthetic infiltration of the iliac crest is associated with a pain reduction compare with placebo. Some studies have shown the benefit of a TAP (transversus abdominal block) for postoperative analgesia after iliac crest bone graft harvest. The TFP block (transversalis fascia plane block) has been recently described. Considering the nerves trajectories, the TFP block is probably anatomically the most appropriate block for analgesia after iliac crest bone graft harvest. The aim of this study is therefore to assess the benefit of an ultrasound TFP block for analgesia after iliac crest bone graft harvest compare with local anesthetic infiltration Design is prospective, randomized, double blind, controlled study

Interventions

DRUGTFP block ropivacaine

DRUGropivacaine infiltration of the iliac crest bone

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \> 18 years * Patients scheduled for iliac crest bone graft harvest during upper or lower limb surgery

Exclusion criteria

* Allergy to ropivacaine, propofol, paracetamol, remifentanil, morphine, cisatracurium, ketoprofene, nefopam * Weight \< 50 kg * Pregnancy * Severe psychiatric disorder * Paraplegia or tetraplegia * Spinal anesthesia * Contra indication to ketoprofene: age ≥ 75 years, renal insufficiency (creatinine clearance \< 50 ml/min), active gastric ulcer, past of asthma with NSAID * Contra indication to nefopam: severe cardiac insufficiency, glaucoma, prostate hypertrophy, epilepsy * Contra indication to paracetamol: severe hepatic insufficiency * Severe respiratory insufficiency * Abnormal hemostasis or anticoagulant treatment * Chronic use of morphine

Design outcomes

Primary

Measure	Time frame
Morphine consumption 24 hours after the surgery	24 hours

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026