Autonomic Responses During the Valsalva Maneuver and Deep Breathing Test Depend on the Experimental Setup

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02397681

Enrollment

Registered

2015-03-25

Start date

2015-01-31

Completion date

2015-08-31

Last updated

2018-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autonomic Nervous System Diseases

Brief summary

The purpose of this study is to determine the effects of procedural differences during the Valsalva maneuver and deep breathing test in autonomic nervous system testing.

Interventions

OTHERAutonomic Function Testing

Autonomic nervous system index assessed with Task Force Monitor (CNSystems Medizintechnik AG, Graz, Austria)

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* male * ≥ 18 year * normal ECG-12

Exclusion criteria

* any known disease * smoking * any intake of regular medicine

Design outcomes

Primary

Measure	Time frame
Blood pressure changes to cardiovascular adrenergic activation	3 hours
Heart rate changes to parasympathetic activation	3 hours

Secondary

Measure	Time frame
Expiratory pressure during the Valsalva maneuver	3 hours
Expiratory duration during the Valsalva maneuver	3 hours
Air volume exchanged per respiratory cycle during deep respiration	3 hours

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026