Hiatus Hernia
Conditions
Brief summary
Retrospective analysis for HRM measurements using liquid swallows and a test meal for the presence of hiatal hernia. The investigators will correlate hernia descriptions with presence of acidic reflux and clinical complaints.
Detailed description
We will retrospectively analyze all patients referred to hour unit for high-resolution esophageal manometry. These patients have been tested using liquid swallows and a test meal. We will analyze the HRM measurements for presence of manometric signs of hiatal hernia and determine predictive factors for hernia presence. We will correlate hernia description versus presence of acid reflux, clinical complaints and HRM measurements.
Interventions
high resolution esophageal manometry using liquid and solid swallows and a test meal.
Sponsors
University of Zurich
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients referred to our functional lab for esophageal high-resolution manometry from January 2013 - December 20165 * Lack of documentation of patient preferences against usage of medical data for biomedical research * Male and female patients ≥18 years of age
Exclusion criteria
* Age under 18 years * Patient's wishes against scientific use of their clinical data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effects of hernia type (consistent hernia, transient hernia and no hernia, as specified bellow) on reflux symptoms | 1 months |
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy for hernia diagnosis by HRM for sitting, and recumbent position, free drinking and test meal. | 1 hour |
| Correlation of pH-impedance measurements (if available) with manometric and clinical data. | 1 hour |
| Correlation of various measurements describing esophageal motility according to Chicago classification with type of hernia, clinical symptoms and pH-impedance measurements | 1 hour |
| Differences in hernia size between sitting and recumbent position as well as between liquid swallows, free drinking and test meal. | 1 hour |
| Correlation of body measurements (body mass index, BMI, waist circumference) of patients with type of hernia, clinical symptoms and pH-impedance measurements | 1 hour |
| Correlation of visceral sensitivity (determined by balloon inflation) with reflux symptoms | 1 hour |
| Prediction of reflux symptoms using a model including hernia and esophageal peristalsis characteristics, visceral sensitivity (balloon inflation) and anthropometric measurements | 1 hour |
| Correlation of hernia diagnosis and hernia size according to imaging exams (if available: CT scan, fluoroscopy) and endoscopy (if available) with hernia diagnosis by HRM | 1 hour |
Countries
Switzerland
Outcome results
None listed