Acne Scar
Conditions
Keywords
acne scar, fractional carbon dioxide laser, platelet rich plasma
Brief summary
Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar
Detailed description
Platelet Rich Plasma may relieve the adverse effect of laser treatment. and it can be expected to improve acne treatment result.
Interventions
PROCEDUREfractional carbon dioxide laser with platelet rich plasma
fractional carbon dioxide laser followed by platelet rich plasma injection
PROCEDUREfractional carbon dioxide laser with NS
fractional carbon dioxide laser followed by normal saline injection
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* moderate to severe acne scar
Exclusion criteria
* taken procedures for acne scar within 6 months * underlying diabetes mellitus, keloid, or malignancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Global assessment of acne scar | 12 weeks | 5-point grading of acne scar |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ECCA (échelle d'évaluation clinique des cicatrices d'acné) | 12 weeks | quantitative analysis of acne scar |
| adverse effect assessment | 12 weeks | adverse effect assessment - erythema index, Epithelization Scale (0-12 point) |
Countries
South Korea
Outcome results
None listed