Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

Influence of Periodontal Diseases on Hemodynamic and Molecular Vascular Parameters in Patients Suffering of Hypertension

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02394860

Enrollment

Registered

2015-03-20

Start date

2015-04-30

Completion date

2024-02-29

Last updated

2025-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Periodontitis, Hypertension

Brief summary

The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

Interventions

OTHERecho Doppler lower limbs

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* -Men- \>40 years * moderate and severe generalized chronic periodontitis * Former diagnosis of hypertension * \>12 teeth

Exclusion criteria

* \>70 years * smokers (\>10 cig/day) * body mass index\>30 * Need of antibioprophylaxis * Medical treatment including anti-inflammatory drugs and/or antibiotics * Refractory form of hypertension- aggressive periodontitis

Design outcomes

Primary

Measure	Time frame
Measuring the thickness of the intima-media	15 days

Secondary

Measure	Time frame
Evaluation of anatomical changes that may occur at the arterial level	Within 15 days after inclusion

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026