Household Air Pollution and Pregnancy Outcome

Conditions

Pregnancy

Brief summary

Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.

O.A. Deji-Abiodun, Babatunde Adedokun, Donee Alexander, Anindita Dutta, Tope Ibigbami et al. (10 authors)

PLoS ONE2022-07-283 citations

10.1371/journal.pone.0272053

Household air pollution, ultrasound measurement, fetal biometric parameters and intrauterine growth restriction

Anindita Dutta, Donee Alexander, Theodore Karrison, Oludare Morhasson-Bello, Nathaniel R. Wilson et al. (18 authors)

Environmental Health2021-06-2318 citations

10.1186/s12940-021-00756-5

Randomized Controlled Ethanol Cookstove Intervention and Blood Pressure in Pregnant Nigerian Women

Donee Alexander, Amanda Northcross, Nathaniel R. Wilson, Anindita Dutta, Rishi Pandya et al. (12 authors)

American Journal of Respiratory and Critical Care Medicine2017-03-0692 citations

10.1164/rccm.201606-1177oc

Interventions

OTHERClean Cookstove

Ethanol

OTHERTraditional Cookstove

Firewood / Kerosene

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

No minimum to 35 Years

Healthy volunteers

No

Inclusion criteria

* Pregnant women who present to the hospital * Who cook exclusively with either kerosene or firewood * Before the fourteenth week of pregnancy as determined by ultrasound imaging

Exclusion criteria

* Smoking women or women with smoking family members * Women with a high-risk pregnancy defined as: * Women with uncontrolled hypertension * Women greater than 35 years old carrying their first child * Women having triplets or more * Women who have had a previous C-section * Women carrying babies with fetal abnormalities or as determined by the obstetrician.

Design outcomes

Primary

Measure	Time frame	Description
Adverse Pregnancy Outcomes	At birth	(first trimester miscarriages, intrauterine growth retardation, low birth weight (300gm less weight in controls relative to intervention group, premature deliveries (deliveries before 37 weeks of pregnancy) and still births.

Secondary

Measure	Time frame	Description
Reduction in personal exposure to PM2.5, CO and PAH	At birth	Reduction in personal exposure to PM2.5, CO and PAH in the Ethanol intervention group relative to the control (kerosene/firewood) group

Countries

Nigeria

Outcome results

None listed