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Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques

Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02393001
Enrollment
50
Registered
2015-03-19
Start date
2015-05-31
Completion date
2017-10-03
Last updated
2019-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melanoma

Keywords

skin cancer, suspicious lesion, skin biopsy, noninvasive, screening

Brief summary

The purpose of this research study is to determine if a very sensitive chemistry lab analyzer can be used to smell a skin cancer (like melanoma) similar to some dogs.

Detailed description

Types of skin cancer, like melanoma, are likely to spread and are becoming increasingly common. At this time, healthcare providers look at patient's skin and remove a sample of suspicious areas of the skin (biopsy) to test for cancer. This research study will inspect cotton and cloth swabs of normal skin and suspicious areas of the skin that are going to be biopsied just before the biopsy. The swabs will be looked at with a very sensitive chemistry lab analyzer to see if the lab analyzer can confirm conventional lab test findings.

Interventions

OTHERDermatology patients

Cleanse an area of unafflicted (control) skin with a cotton 2 x 2 dampened with saline.

Sponsors

University of Florida
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years of age or older * Seen at the dermatology clinic & determined to need a skin biopsy of a suspicious lesion

Exclusion criteria

* \< 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Compare the off line spectral analyses of saline and alcohol skin swabs of normal control, melanoma negative and melanoma positive skin biopsies.1 dayDetermine if the melanomas have unique identifying spectra that might be applied to noninvasive melanoma skin cancer screening in lieu of taking a biopsy

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026