Diabetic Retinopathy
Conditions
Brief summary
Clinical evaluation of noninvasive OCT Angiography using a Zeiss OCT Prototype to replace fluorescein angiography.
Detailed description
Fluorescein angiography (FA) is the standard and generally accepted method to identify vascular features in the retina, detecting capillary dropout and neovessel growth. Its value is undeniable and is a routine ophthalmological examination. However, it requires intravenous injection of fluorescein, which can cause nausea, vomiting and, rarely, anaphylaxis and death. New OCT angiography methods can detect, noninvasively red blood cells flow and, therefore, identify well the retinal vasculature. It is crucial and of major interest to evaluate the clinical utility of this new methodology comparing this information with the one obtained from fluorescein angiography.
Interventions
None listed
Sponsors
Association for Innovation and Biomedical Research on Light and Image
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* All patients with clinical indication for fluorescein angiography in their clinical practice
Exclusion criteria
* Subjects with a pacemaker of similarly critical electronic device * Subjects with severe ocular media opacities * Subjects with corneal abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison between examination techniques on the detection of morphological changes in the retina (such as vessels morphology, vascular ischemia, retinal neovascularization, choroidal neovascularization, and other vascular abnormalities). | Single Visit |
Countries
Portugal
Outcome results
None listed