Neuromuscular Blockade, Pain Management
Conditions
Keywords
analgesia, nerve block, Total knee replacement
Brief summary
The purpose of the study is to determine whether the association of sciatic nerve block to continuous adductor canal block is effective in the treatment of total knee arthroplasty post operative pain .
Interventions
PROCEDUREContinuous femoral nerve block
PROCEDUREContinuous adductor canal block
PROCEDUREinfragluteal Sciatic nerve block
DRUGRopivacaine 0.2%
DRUGSaline
Sponsors
Institut Kassab d'Orthopédie
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Elective unilateral TKA, * Planned continuous spinal anesthesia , * Ability to follow study protocol, * American Society of Anesthesiologists class 1 to 3.
Exclusion criteria
* Contraindication for neuraxial anesthetic, * Chronic opioid use (defined as daily or almost daily use of opioids for \>3 months), * Hypersensitivity and/or allergies to any of the study medications, * Intraoperative use of volatile anesthetics, * Preexisting neuropathy on the operative limb, * Contraindications to a femoral, adductor canal or Tibial nerve block.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total Opioid-consumption | 8 hours postoperative | Cumulative opioid consumption : converting oral, intravenous, and patient-controlled analgesia PCA opioid to morphine equivalent |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| NRS pain score during movement | 0,1,2,4,6,8,12,24 and 48 hours postoperative | NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale, during physiotherapy. |
| NRS pain score after 10 meters of walk or maximum walked distance | 8, 24 and 48 hours postoperative | NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale after 10 meters walk (if enable after maximum walked distance). |
| Ability to walk | 8, 24 and 48 hours postoperative | The ability of the patient to stand up and walk 3 meters. |
| NRS pain score at rest | 0,1,2,4,6,8,12,24 and 48 hours postoperative | NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale at rest. |
| The 10-m walk test | 8, 24 and 48 hours postoperative | time it takes the patient to walk a distance of 10 m as quickly as possible |
| patient satisfaction | 8, 24 and 48 hours postoperative | patient interviewed, using a scale of 0-10, 0 not satisfied and 10 being the most satisfied |
| TUG Test | 8, 24 and 48 hours postoperative | The TUG test measures the time it takes a patient to stand up from a chair, walk a distance of 3 m, and return to the chair |
Contacts
Primary ContactKarim Raies, M.D
Outcome results
None listed