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ARC in Hemorrhagic Stroke

Augmented Renal Clearance in Hemorrhagic Stroke Patients Admitted to the Neurosciences Intensive Care Unit

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02386202
Enrollment
80
Registered
2015-03-11
Start date
2015-01-31
Completion date
2015-08-31
Last updated
2015-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Augmented Renal Clearance, Hemorrhagic Stroke

Brief summary

To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.

Interventions

OTHERNo intervention

No interventions

Sponsors

University of North Carolina, Chapel Hill
Lead SponsorOTHER

Study design

Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adults ≥ 18 years * Patients with hemorrhagic stroke * Anticipated length of stay in the neuroscience intensive care unit \> 48 hours * Informed consent provided by the patient or by the patient's designated medical proxy

Exclusion criteria

* Pregnancy * Patients with pre-existing renal dysfunction (chronic kidney disease stages 3 - 5) * Patients receiving renal replacement therapy * Patients with an admission serum creatinine \> 1.4 mg/dL * Patients with non-aneurysmal subarachnoid hemorrhage * Patients with history of nephrectomy or body mass index \< 18 kg/m2

Design outcomes

Primary

MeasureTime frameDescription
To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic strokeOver neurosciences intensive care unit stayDaily 8-hour urine collections will be performed to directly measure creatinine clearance up to ICU discharge

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026