Incidence and Reasons for Preoperative Anemia in Elective Lower Joint Arthroplasty

Incidence and Reasons for Preoperative Anemia in Elective Lower Joint Arthroplasty - A Descriptive Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02385409

Enrollment

900

Registered

2015-03-11

Start date

2013-05-31

Completion date

2015-05-31

Last updated

2015-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee

Keywords

Patient Blood Management, Preoperative anemia, Hip replacement, Knee replacement

Brief summary

Preoperative anemia is an independent risk factor for the need for allogeneic transfusion during surgery and increased postoperative morbidity. Treatment of preoperative anemia is recommended. However the type of preoperative anemias in elective hip- and knee surgery has only been sparsely studied. This observational study aims to investigate the incidence and type of anemias prior to elective hip- and knee arthroplasty.

Detailed description

Preoperative anemia is an independent risk factor for the need for allogeneic transfusion during surgery and increased postoperative morbidity. In elective orthopedic surgery, international guidelines recommends treatment of preoperative anemia including the use of Iron supplements for anemias associated with iron deficiency. In addition, low iron stores in both anemic and non-anemic patients may delay postoperative hemoglobin recovery. However, the reasons for preoperative anemia and the prevalence of patients with low iron stores have only been sparsely studied in elective hip- and knee arthroplasty. This observational study aims to investigate the incidence and type of anemias prior to elective hip- and knee arthroplasty.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \> 18 years * Scheduled for elective primary hip- or knee replacement.

Exclusion criteria

* Not possible to obtain preoperative blood sample.

Design outcomes

Primary

Measure	Time frame	Description
Anemia Classification - Biochemical classification from preoperative venous blood samples	Date of preoperative blood sampling	Biochemical classification from preoperative venous blood samples

Secondary

Measure	Time frame	Description
Prevalence of Anemia according to WHO definitions	Date of preoperative blood sampling	According to WHO definitions
Proportions of non-anemic patients with low irons stores	Date of preoperative blood sampling	Low Ferritin or Transferin saturation (TSAT)

Countries

Denmark

Outcome results