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Effect of a Protein-enriched Drink on Muscle Function

Effect of a Protein-enriched Drink on Muscle Function Recovery Following an Acute High Intensity Exercise Bout

Status
UNKNOWN
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02385357
Acronym
SPORTEUS
Enrollment
12
Registered
2015-03-11
Start date
2015-02-28
Completion date
2015-12-31
Last updated
2015-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contracture

Keywords

Muscle function, Anaerobic power, Muscle damage

Brief summary

There is no conclusive evidence about the effect of intake of protein-enriched drink after and acute high intensity exercise bout on muscle function and damage. The investigators aimed to study the effect of a protein-enriched drink on muscle function recovery following an acute high intensity exercise bout. The present counterbalanced, crossover, and double blind study will involve a total of 12 active men.

Detailed description

Participants will run downhill (-10%) during 30 min at a intensity equivalent to 75-80% of their maximum heart rate (previously determined). After the exercise bout, participants will have either the placebo or the experimental drink. The investigators will measure muscle function and damage-related parameters right after the exercise as well as the three following days. This protocol will be repeated after a wash out period of 3 weeks, where the participants will have the other drink. The investigators will control exercise and diet three weeks before study entry, during the experimental week as the investigators as during the wash out period.

Interventions

DIETARY_SUPPLEMENTProtein-enriched drink

Participants will drink 330 ml of a protein-enriched drink (6 g/ml of protein) after a high intensity exercise that induce muscle damage (30 min running downhill with a slope of -10º)

Sponsors

Universidad de Granada
CollaboratorOTHER
Puleva Biotech
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Recreational triathletes with 2 years of experience * Maximum oxygen uptake : ≥55 ml/kg/min * Fat mass: 8-20% measured by dual energy x-ray absorptiometry * Not participating in another study * Not having ergogenic aids * Not participating in a weight loss program * Normal electrocardiogram * Participants must be capable and willing to provide consent, understand

Exclusion criteria

and accept the randomized group assignment

Design outcomes

Primary

MeasureTime frameDescription
Isometric muscle strengthChange from pre- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drinkIsometric muscle strength of lower limbs at 90% angle.

Secondary

MeasureTime frameDescription
Power output assessed with the 30sec. Wingate anaerobic testChange from post- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drinkPower output will be assessed with the 30sec. Wingate anaerobic test.
Creatine kinaseChange from post- protein-enriched drink to 24, 48 hrs post- protein-enriched drinkCreatine kinase will be assessed after the protein-enriched drink to assess muscle recovery after a high intensity exercise bout
Muscle soreness of lower limbs self-reported by a visual anagogic scale and with an algometer score.Change from post- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drinkMuscle soreness of the lower limbs will be self-reported by a visual anagogic scale and with an algometer score.
Resting metabolic rateChange from pre- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drink
Time limit (time that the participant is able to run 90% of his determined maximum aerobic velocity)24hrs after protein-enriched drinkWe will measure the time that the participant is able to run 90% of his determined maximum aerobic velocity
Urine CreatinineChange from post- protein-enriched drink to 24, 48 hrs post- protein-enriched drinkConcentration of creatinine in urine will be assessed after the protein-enriched drink to assess muscle recovery after a high intensity exercise bout

Countries

Spain

Contacts

Primary ContactFederico Lara, PhD
Federico.LaraVilloslada@puleva.es0034958240100

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026