Brain Injuries, Stroke
Conditions
Brief summary
C8 sciences program is a cognitive training program mainly developed for the students, and the effectiveness is well established. The aim of this trial is to assess clinical efficacy of the program for cognitive rehabilitation of the patients with stroke or brain injury.
Interventions
1000 minutes of computerized cognitive rehabilitation with C8 sciences program
Same amount of conventional cognitive rehabilitation
Sponsors
Hanyang University
National IT Industry Promotion Agency, Republic of Korea
National Rehabilitation Center, Seoul, Korea
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Participants with stroke or brain injury * Cognitive deficits
Exclusion criteria
* Uncontrolled medical comorbidities * Not able to perform outcome measurements * Aphasia, which hamper communication * Pre-diagnosed psychological or other neurological disease not relevant to stroke or brain injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline Cambridge Neuropsychological Test Automated Battery(CANTAB) Spatial working memory at 34 th intervention | Baseline, 34th day from baseline |
| Change from baseline CANTAB Rapid Visual information Processing at 34 th intervention | Baseline, 34th day from baseline |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Korean Mini-Mental State Examination (K-MMSE) | Baseline, 34th day from baseline | — |
| Korean activities of daily living (K-ADL) | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Attention Switching Task | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Stoking of Cambridge | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Emotion Recognition Task | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Stop Signal Task | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Spatial working memory | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Rapid Visual information Processing | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Motor control task | Baseline, 34th day from baseline, 64th day from baseline | — |
| Geriatric depression scale | Baseline, 34th day from baseline | Older participants |
| CANTAB reaction time | Baseline, 34th day from baseline, 64th day from baseline | — |
| Korean instrumental activities of daily living (K-IADL) | Baseline, 34th day from baseline, 64th day from baseline | — |
| clinical dementia rating scale (CDR) | Baseline, 34th day from baseline | — |
| Stroke impact scale | Baseline, 34th day from baseline | — |
| Subjective memory complaint questionnaire | Baseline, 34th day from baseline, 64th day from baseline | — |
| NIH toolbox | Baseline, 17th day from baseline, 34th day from baseline, 64th day from baseline | — |
| Autobiographical memory | Baseline, 34th day from baseline | — |
| Trail making test (A/B) | Baseline, 34th day from baseline, 64th day from baseline | — |
| Trail making test - Black and White | Baseline, 34th day from baseline, 64th day from baseline | — |
| CANTAB Paired Associated Learning | Baseline, 34th day from baseline, 64th day from baseline | — |
| Beck depression index | Baseline, 34th day from baseline | — |
Countries
South Korea
Outcome results
None listed