Wound Healing
Conditions
Brief summary
The primary objective of this study is to compare the efficacy of hydrogen peroxide versus normal saline in postoperative care of sutured wounds. Subjects will be randomly assigned to standard of care hydrogen peroxide or standard of care normal saline in postoperative care of sutured wounds followed by applying petroleum jelly and sterile gauze bandage. Data will be collected at day 0 and between days 7 to14. Subjects will provide irritation scale rating (0-4) with 0 being none/absent and 4 being severe/extreme.
Interventions
DRUG3% H2O2 solution
DRUG0.9% normal saline
Sponsors
Northwestern University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. Patients who are undergoing sutured wound after dermatologic procedure. 2. Males and females ages 18-65 years old. 3. Patients who are in good health. 4. Willingness and the ability to understand and provide informed consent and communicate with the investigator/study staff.
Exclusion criteria
1. History of keloids or hypertrophic scars. 2. History of bleeding tendency or coagulopathy. 3. Pregnant or lactating or intends to become pregnant in the next 3 months. 4. Active skin disease or skin infection in the treatment area. 5. Unable to understand the protocol or to give informed consent. 6. Any other condition that would, in the professional opinion of the investigator, potentially affect response or participation in the clinical clinical study, or would pose as an unacceptable risk to the subject.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Irritation scale rating from 1-2 weeks compared to baseline | Baseline and 1-2 weeks | Subjects will provide irritation scale rating (0-4) with 0 being none/absent and 4 being severe/extreme. |
Countries
United States
Outcome results
None listed