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Postprandial Differences After Herring and Beef

Postprandial Plasma Nutrient Differences Between Baked Beef, Baked Herring and Pickled Herring.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02381613
Enrollment
17
Registered
2015-03-06
Start date
2012-01-31
Completion date
2015-03-31
Last updated
2015-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Disease

Keywords

Fish, Herring, Meat, Beef

Brief summary

While observational studies often find that diets rich in fish reduce the risk of disease, and that diets including a high intake of red meat are associated with increased risk of cardiovascular disease and cancer, the difference in health effects between red meat and fish are rarely researched in intervention studies. The investigators hypothesise that the post-prandial plasma response of lipids and markers of cardiovascular disease risk will be more favourable after intake of herring compared to beef. In addition, while pickling herring in a brine/sugar solution is a common form of preparation, little is known if there is a difference in potential health effects based on the preparation of herring. The investigators will compare baked and pickled herring to understand if preparation is potentially an important factor to be considered when looking at intake of fish and health.

Interventions

OTHERBaked beef

A meal based on baked beef

OTHERBaked herring

A meal based on baked herring

OTHERPickled herring

A meal based on pickled herring

Sponsors

Oy Foodfiles Ltd
CollaboratorOTHER
Chalmers University of Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
MALE
Age
35 Years to 67 Years
Healthy volunteers
Yes

Inclusion criteria

* Male * 35-67 years * BMI \>30 kg/m2 * Normally eats lunch and dinner

Exclusion criteria

* Smoke or oral tobacco use * Use of prescription or recreational drugs likely to interfere with primary outcome * Change in body weight in the month prior to the study * Abnormal blood biomarker values (assessed by a clinician)

Design outcomes

Primary

MeasureTime frame
Omega-3 fatty acidsArea under the curve between 0 and 7 hours

Secondary

MeasureTime frame
Plasms insulinArea under the curve between 0 and 7 hours
Plasma triglyceridesArea under the curve between 0 and 7 hours
Plasma lipoprotein-cholesterolArea under the curve between 0 and 7 hours
Plasma vitamin DArea under the curve between 0 and 7 hours
Plasma metabolomic profileArea under the curve between 0 and 7 hours
Urinary metabolomicsArea under the curve between 0 and 7 hours

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 15, 2026