The ADRB3 Receptor in Pregnancy

The ADRB3 Adrenergic Receptor - a Possible New Target for Controlling Pre-eclampsia and Hypertension in Pregnancy and Uterine Contractions in Non-pregnant and Pregnant Myometrium

Status

Suspended

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02381106

Enrollment

Registered

2015-03-06

Start date

2014-11-30

Completion date

2029-12-31

Last updated

2023-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy Complications

Keywords

arterial contractility, Uterine contractility

Brief summary

The primary overall objective of this study is to characterize the levels of and compare levels of the ADRB3 receptor in human non-pregnant myometrium, pregnant myometrium at different time points in pregnancy, in normal and dysfunctional labor and also to measure levels and expression of these receptors in placental arteries at different maturation statuses of placenta and in pre-eclampsia/hypertension

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Women undergoing cesarian section

Exclusion criteria

* Interkurrent diseases

Design outcomes

Primary

Measure	Time frame
characterization of the levels of the ADRB3 receptor in human pregnant myometrium	1 month

Countries

Sweden

Outcome results