Effect of Moderate Alcohol Consumption to Cognitive Functioning After Roux-en Y Gastric Bypass

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02380950

Enrollment

Registered

2015-03-05

Start date

2013-06-30

Completion date

Unknown

Last updated

2015-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Consumption, Bariatric Surgery, Cognitive Function

Brief summary

Objectives: Alcohol metabolism is changed in gastric bypass patients, leading to faster resorption and higher alcohol peak concentrations in blood. Because of stronger alcohol effects after gastric bypass we suggest that also general cognitive function is stronger impaired. Materials and Methods: We included 28 females (12 gastric bypass patients, 8 obese and 8 normal weight subjects) in the study. Each participant had to drink 250 ml white wine. Directly before, 10-30 min after and 45-65 min after wine consumption cognitive functions were tested by test battery for attentional performance (TAP) from Zimmermann and Fimm. During the whole examination breath-alcohol-contents (BACs) were measured every 5 minutes with breathalyser Dräger Alcotest 7510.

Interventions

BEHAVIORAL250 ml alcohol consumption

Each participant had to drink 250 ml white wine. Directly before, 10-30 min after and 45-65 min after wine consumption cognitive functions were tested by test battery for attentional performance (TAP) from Zimmermann and Fimm. During the whole examination breath-alcohol-contents (BACs) were measured every 5 minutes with breathalyser Dräger Alcotest 7510.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

Gastric bypass group: * women * preOP BMI \>35 kg/m² * time since bariatric surgery \> 1 year * age 18-60 years * moderate drinking habits obese group: * women * BMI \>35 kg/m² * age 18-60 years * moderate drinking habits normal weight group: * women * BMI 18.5 - 25 kg/m² * age 18-60 years * moderate drinking habits

Exclusion criteria

* men * patient does not drink wine * usage of psychotropic drugs * alcoholic * pregnancy

Design outcomes

Primary

Measure	Time frame
Change in reaction time after alcohol consumption	Change measures (baseline, 10 min, 45 min)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026