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Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02378337
Acronym
pet-ct
Enrollment
335
Registered
2015-03-04
Start date
2014-09-30
Completion date
2016-03-31
Last updated
2017-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hodgkin Disease, Malignant Melanoma of the Skin, Malignant Neoplasm of Breast, Malignant Neoplasm of Bronchus and Lung, Malignant Neoplasm of Colon, Malignant Neoplasm of Small Intestine, Non-Hodgkin Lymphoma, Follicular (Nodular), Secondary Neoplasm Malignant and Unspecified Lymph Nodes

Brief summary

Identify the best combination of predictive variables that influence ionizing radiation dose and improved image quality through analysis and quantification of PET-CT images in simulators and patients.

Interventions

OTHERImage quantify

Will be observed all patients who perform PET / CT examinations, independent of clinical indication, in nuclear medicine at Hospital Sao Rafael. Those who show interest in participating in the study, will be provided free and informed consent form (ICF) for your appreciation. This evaluation will serve for analysis and quantification of PET-CT images.

Sponsors

Hospital Sao Rafael
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Healthy volunteers; * Both genders; * Age over 18 years; * Clinical indication for PET-CT scan.

Exclusion criteria

* Pregnant women; * Patients who have lesions in the liver metabolically active whether primary or metastatic; * Patients with movement difficulties.

Design outcomes

Primary

MeasureTime frameDescription
Correlation of body weight with the variation coefficient (image noise).360 secondsThe image noise will be measured by VOI (Volume Of Interest) in the images. The units of measure will be kilograms (kg) for body weight, and percentage for the variation coefficient.

Secondary

MeasureTime frameDescription
Correlation of dose-regimen with the variation coefficient (image noise).360 secondsThe dose-regimen will be calculated based on radiation dose and body surface. The image noise will be measured by VOI (Volume Of Interest) in the images. The units of measure will be MegaBecquerel per kilogram (MBq/kg) for dose-regimen, and percentage for the variation coefficient.
Correlation of acquisition protocol time with the variation coefficient (image noise).360 secondsImages will be acquired every 30 seconds until a maximum of 360 seconds. The image noise will be measured by VOI (Volume Of Interest) in the images. The units of measure will be seconds for the acquisition time, and percentage for the variation coefficient.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026