Evaluation of Dentin Hypersensitivity Using Glass Ionomer Cements

Evaluation of the Effectiveness of Dentin Hypersensitivity Treatment Using Glass Ionomer Cements: A Randomized Clinical Trial

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02378129

Enrollment

Registered

2015-03-04

Start date

2014-04-02

Completion date

2015-04-01

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Hypersensitivity

Keywords

Dentin Sensitivity, Dentin Desensitizing Agents, Glass Ionomer Cements, Randomized Controlled Trial

Brief summary

The aim of this randomized, double-blind, split-mouth clinical trial is to evaluate and compare the desensitizing efficacies of the resin-modified glass ionomer cement ClinproTM XT (3M ESPE, Minnesota, USA) and the conventional glass ionomer cement Vidrion R (SS White, Gloucester, UK) at 2-year follow-up.

Detailed description

Subjects will require to have at least two teeth in different hemiarchs with dentin hypersensitivity. Teeth will be randomized into 2 groups, receiving either Clinpro XT or the conventional glass ionomer cement Vidrion R. Prior to the desensitizing treatment (baseline), painful symptoms will be assessed by tactile and air blast tests using the Visual Analogue Scale (VAS). Treatment evaluations will be conducted up to 2-year post-treatment.

Interventions

DRUGResin-modified glass ionomer cement Clinpro XT

Clinpro XT (3M ESPE, Minnesota, USA)

DRUGGlass Ionomer cement Vidrion R

Vidrion R (SS White, Gloucester, UK)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

28 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Male and female subjects between 18 and 70 years old * At least 2 teeth with dentin hypersensitivity in two different hemiarchs * Dental elements with hypersensitivity without any pulp alteration * People who are not taking any medication and women who are not pregnant * Patients without eating disorders or very acidic diets.

Exclusion criteria

* Teeth with hypersensitivity that presented extensive or unsatisfactory restorations, fractures, periodontal alterations, caries lesions, orthodontic brackets, endodontic treatments, pulp alterations. * Subjects who received any desensitizing therapy during the last 3 months * Subjects being under analgesics/anti-inflammatory drugs at the time of the study * Teeth with hypersensitivity and non-carious cervical lesions

Design outcomes

Primary

Measure	Time frame	Description
Pain Scores as measured by the Visual Analog Scale (VAS)	Change from Baseline in Pain Scores at 20 minutes; at 7, 15, 21, 30 days; and after 3, 6, 12, 24 months.	Tactile and air blast tests to evaluate pain with VAS

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026