Acute Kidney Injury
Conditions
Brief summary
The research study will investigate the longitudinal cognitive outcomes in subjects admitted as children diagnosed with sepsis who may have had acute kidney injury. Each subject will be contacted 2-15 years after their incident admission in order to solicit responses to a functional and cognitive quality of life survey. Children admitted during the same time frame that did not have kidney injury will also be surveyed.
Detailed description
250 subjects with a prior admission for pediatric sepsis will be contacted 2-15 years following the incident admission in order to complete a survey to assess their overall quality of life. Children will be administered the Pediatric Quality of Life (PedsQL) survey with a parental section to allow for parental response. Adult subjects will take the adult version of the PedsQL.
Interventions
OTHERPediatric Quality of Life (Peds QL) Survey
The subjects will be administered the Peds QL survey. Children will also have a parental section for parental response. This is NOT an interventional study.
Sponsors
American Society of Nephrology
University of Florida
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
2 Years to 36 Years
Healthy volunteers
No
Inclusion criteria
* Subjects may be adults or children who were admitted to the hospital with a severe infection between January 1998 to December 2014. * Consent from adult or parent/guardian of child to participate in study. * Assent from subjects between 7 and 17 years of age.
Exclusion criteria
* Failure or inability to complete the survey * Participant is unable to understand written or spoken English * Subjects between 7 and 17 years of age unwilling to assent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall health related quality of life score (HRQOL) | Baseline | Scale 0-100 |
Countries
United States
Outcome results
None listed