Healthy
Conditions
Keywords
clitoris, sexuality, vascularization, doppler, ultrasound, reference, female, Pilot Projects, Vagina/ultrasonography, Urethra/ultrasonography, Regional Blood Flow/physiology, Arteries/ultrasonography, Clitoris/ultrasonography, Reference values, Clitoris/blood supply
Brief summary
Monocentric pilot interventional study. The aim of the study is to assess clitoral doppler ultrasonographic parameters in a population of sexually healthy volunteer women in order to obtain reference values. Psychobiological correlates of female sexual function will also be studied through hormonal testing and psychological evaluation.
Interventions
OTHERclitoral, transvaginal and transrectal ultrasound
Doppler Ultrasound assessment of clitoral hemodynamics will be performed in all subjects. Transvaginal and transrectal ultrasound will be performed in subjects giving their consent to these procedures.
Sponsors
University of Florence
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* sexually healthy * evidence of a personally signed and dated informed consent.
Exclusion criteria
* any uncontrolled or unstable, acute or chronic disease * alcohol or drugs abuse * sexual dysfunction * any overt psychiatric or psychological condition assessed through psychological evaluation and/or self-administered validated questionnaires.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clitoral artery peak systolic velocity and acceleration | baseline | This will not be evaluated in different time frames but evaluated in order to assess reference values in sexually healthy women and compared with subjects with sexual dysfunction. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| General psychopathology assessed through the Middlesex Hospital Questionnaire (MHQ) | baseline | See above |
| Body image is investigated through the Body Uneasiness Test (BUT) | baseline | — |
| Measurement of the thickness of the urethrovaginal space | baseline | — |
| Female sexual function assessed through the Female Sexual Function Index (FSFI) | baseline | — |
| Hormonal parameters (17β-estradiol, total testosterone, LH, FSH, TSH, PRL, delta-4-androstenedione, DHEAS, 17-Hydroxyprogesterone, SHBG) | baseline | — |
| Metabolic parameters (total cholesterol, HDL, triglycerides, glycemia, insulin, glycated hemoglobin) | baseline | — |
| Measurement of the thickness of the endometrial lining | baseline | — |
Countries
Italy
Outcome results
None listed