Non-invasive Determination of Anemia in Children With Renal Failure

A Non-invasive Device to Determine Iron Deficiency Anemia in Children of Different Age Groups With Renal Failure

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02369237

Enrollment

Registered

2015-02-23

Start date

2012-04-30

Completion date

2012-06-30

Last updated

2015-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Failure

Brief summary

Anemia and inflammation are very common in patients with renal diseases. The most common procedure to detect anemia is to determine blood hemoglobin concentrations. The Haemospect® is a portable device for non-invasive hemoglobin determination that works with a sensor that is applicable in infants and adults alike. The objective of this trial is to collect spectra with the non-invasive Haemospect® device in children of different age groups with renal failure and different hemoglobin concentrations. In parallel, corresponding hemoglobin values shall be obtained invasively to form the basis for the development of an algorithm for the device. To determine inflammation, the frequencies of vasomotion and oxygenation of the tissue are measured non-invasively with the Haemospect®. Various blood parameters for iron and inflammation will also be determined, such as ferritin, hepcidin, transferrin, serum iron, white blood cell count and CRP.

Interventions

None listed

Study design

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* all children in treatment for renal insufficiency in FUNDANIER

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame	Description
Hemoglobin	1 day	—
Iron parameters	1 day	Serum iron, ferritin, transferrin, transferrin saturation, TIBC, hepcidin
Inflammation parameters	1 day	Ferritin, hepcidin, CRP, white blood cell count, ESR

Secondary

Measure	Time frame	Description
anthropometric data	1 day	weight, height, WAZ, HAZ and WHZ

Outcome results