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Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control

Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control : A Randomized Controlled Trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02369133
Enrollment
60
Registered
2015-02-23
Start date
2013-11-30
Completion date
2014-11-30
Last updated
2015-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section; Dehiscence

Brief summary

The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of morfin-related side effects in patients undergoing cesarean section.

Interventions

DRUGparacetamol

Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group P (n = 30) received 1 g iv paracetamol, patients in group S (n = 30) received 100 ml iv %0.9 NaCl

DRUGPlacebo

Sponsors

Baskent University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Investigator)

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients between the ages of 20-40 years, * ASA physical status 1-2 who underwent elective cesarean surgery during general anesthesia were included in the study

Exclusion criteria

* A history of allergy to any of the study medications (opiod, general anesthetic agents or paracetamol), * history of opioid or paracetamol use, * hepatic or renal failure, * any psychological disorders, * complications during cesarean section and unable to use PCIA device were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Postoperative pain scores measured by visual analog scale (VAS)Postoperative 24 hours

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026