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Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.

Comparison of Sedative Effects of Dexmedetomidine and Propofol on the Clinical Course of Delirium and Neuroinflammation in Patients With SIRS.

Status
Withdrawn
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02366299
Enrollment
0
Registered
2015-02-19
Start date
2015-02-28
Completion date
2018-12-31
Last updated
2019-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium

Brief summary

Assessment of sedative effects of dexmedetomidine and propofol on the clinical course of delirium and neuroinflammation in patients with SIRS using CAM-ICU scale and protein S100b in serum.

Interventions

DRUGDexmedetomidine

Treatment of delirium by dexmedetomidine i.v. infusion

DRUGPropofol

Treatment of delirium by Propofol i.v. infusion

Sponsors

Moscow Regional Research and Clinical Institute (MONIKI)
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* presence of delirium

Exclusion criteria

* presence of Alzheimer's disease * any mental disorder * presence of cancer

Design outcomes

Primary

MeasureTime frame
CAM-ICU scaleup to 5 days

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026