Diabetes Prevention, Obesity Prevention
Conditions
Brief summary
The objectives are to test the acute effects of different bagels containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. We hypothesize that consumption of bagels containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. We also hypothesize that consumption of bagels containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.
Interventions
Sponsors
Saskatchewan Pulse Growers
Alberta Pulse Growers
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Normoglycemic (\<5.6 mmol/L) and normotensive (systolic blood pressure \<140 mm Hg and diastolic blood pressure below \< 90 mm Hg) * BMI of 18.5-29.9 kg/m2
Exclusion criteria
* Restrained eaters * Regularly skip breakfast * Smokers * Those who are active (organized activities or athletic training at a high intensity; ≥ 150 min per week of moderate to vigorous physical activity) * Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year * Those unable to walk for an hour continuously
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma Glucose and Insulin Concentrations | 0-240 | Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits |
| Food Intake | 120 min | Ad-libitum meal |
| Subjective Appetite | 0-240 min | Motivation-to-eat VAS questionnaire |
| Exercise intensity | 60-120 min | Oxygen consumption measured during exercise at 3 time points |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lactate concentration | 60-120 min | Measured before, during, and exercise exercise at 3 time points |
| Palatability | 5 and 260 min | Measured by VAS questionnaire |
| Substrate Oxidation | 60-120 min | Respiratory quotient measured during exercise at 3 time points |
| Physical comfort | 0-240 min | Measured by VAS questionnaire |
| Energy/fatigue | 0 - 240 min | Measured by VAS questionnaire |
| Heart rate | 60-120 min | To monitor exercise intensity and give a measure of fatigue (cardiovascular drift) |
Countries
Canada
Outcome results
None listed