Febrile Neutropenia, Lymphoma, T-Cell, Peripheral
Conditions
Brief summary
Prospective, observational cohort study of peripheral T cell lymphoma. Purpose is to investigate the complication including febrile neutropenia in the era of pegylated G-CSF prophylaxis.
Detailed description
Prospective evaluation of frequencies of febrile neutropenia or infectious complications in a homogeneous population of patients with peripheral T cell lymphoma
Interventions
None listed
Sponsors
Samsung Medical Center
Asan Medical Center
Keimyung University Dongsan Medical Center
Kosin University Gospel Hospital
Dankook University
Soonchunhyang University Hospital
Ajou University School of Medicine
Yeungnam University Hospital
Ulsan University Hospital
Inje University
Chung-Ang University Hosptial, Chung-Ang University College of Medicine
Hallym University Medical Center
Hanyang University Seoul Hospital
Seoul National University Hospital
Pusan National University Hospital
National Health Insurance Service Ilsan Hospital
Hanyang University
Korea Cancer Center Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Treatment naive peripheral T cell lymphoma Subtypes are as followings: Anaplastic large cell lymphoma angioimmunoblastic T cell lymphoma Peripheral T cell lymphoma-NOS Enteropathy-associated T cell lymphoma Hepatosplenic T-cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Primary cutaneous gamma-delta T-cell lymphoma Primary cutaneous CD8+ aggressive epidermotropic lymphoma 2. Scheduled to receive chemotherapy of curative intent 3. 19 years old or over 4. Expected survival is more than 6 months 5. Informed consent
Exclusion criteria
1. Other histology than those described above * Extranodal NK/T cell lymphoma * Other than peripheral T cell lymphoma 2. Other combined malignancy 3. Previous history of chemotherapy or radiation therapy 4. No informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Febrile neutropenia | 2 years after the last enrollment | Incidence and severity of febrile neutropenia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Infectious complication | 2 years after the last enrollment | incidence, severity, microbiology of infection |
Countries
South Korea
Contacts
Primary ContactDong-Yeop Shin, M.D.
Outcome results
None listed