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Outcomes Following Total Knee Arthroplasty

Clinical and Biomechanical Outcomes Following Total Knee Arthroplasty

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02364011
Enrollment
120
Registered
2015-02-16
Start date
2014-11-30
Completion date
2025-06-10
Last updated
2025-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Keywords

Biomechanics, Primary Total Knee Arthroplasty, TKA Bearings, Osteoarthritis, Total Knee Replacement

Brief summary

The purpose of this investigation is to determine both patient-reported and performance-based outcomes, specifically muscle function and kinematic/kinetic outcomes, between four different surgical total knee prostheses in individuals following TKA. Change scores will be determined based on patient-reported outcomes, kinematic/kinetic data, knee extension strength/power, static/dynamic balance control, mobility measures and functional performance testing during functional tasks (i.e. walking, ascending/descending stairs, sit-to-stand). After evaluating the pattern of change in lower-extremity function, the investigators will be better prepared to address residual functional impairments and prognostic factors linked to maximal recovery over two years.

Interventions

None listed

Sponsors

University of Utah
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
40 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* adults \> 40 years of age that are scheduled for primary TKA * if they have had a previous TKA, it needs to have been performed on the opposite leg at least 3 months prior to the current TKA * willing to return for follow-up visits and should be willing and able to be transported from the UOC to the Skeletal Muscle Exercise Research Facility (SMERF), in the Department of Physical Therapy study site for scheduled research follow-up appointments

Exclusion criteria

* adult with previous additional orthopaedic, neurological, visual or surgical conditions that may affect gait or balance

Design outcomes

Primary

MeasureTime frame
Patient Reported Outcome Scores following TKAFollow Up Visits up to 2-Years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026