Echographic Measurement of Skin Thickness

Echographic Measurement of Skin Thickness at the Deltoid and Proximal Forearm in Adults

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02363465

Enrollment

100

Registered

2015-02-16

Start date

2015-01-31

Completion date

2015-06-30

Last updated

2015-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin Thickness

Keywords

skin thickness, high-frequency ultrasound

Brief summary

To optimize a medical device for intradermal injection, knowledge concerning the thickness of epidermis and dermis at the proximal forearm is required. Since scientific knowledge is lacking, the investigators will examine the skin thickness (epidermis and dermis) of adults using imaging technology (High Frequency Ultrasound). The investigators hypothesize that they are able to correlate the thickness of the (epi)dermis to a specific combination of parameters age, gender, and BMI. Based on these results, the investigators can define which needle type and length is needed to correctly perform injections into the dermal layer.

Interventions

OTHEREchographic measurement of skin thickness

(Epi)Dermal thickness at the proximal forearm and the deltoid region will be measured using imaging technology, more specifically high-frequency ultrasound (20-40 MHz) in B-mode (VEVO 2100®, Visual Sonics). This non-invasive measuring technique has already been proven to be accurate. The echographic measurement will be performed on the left and right deltoid region and on two sides of the proximal forearm. Both the dorsal part and the volar/palmar part of the proximal forearm will be investigated. Ultrasound will be executed using gel (Aquasonic®) to optimize imaging.

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy adults * Age: 18-65 years * Dutch-speaking * Caucasian

Exclusion criteria

* Pregnancy or lactating * Using ointment, crème, or gels based on corticoids * Suffering from skin diseases (psoriasis, burning wounds)

Design outcomes

Primary

Measure	Time frame
skin thickness (in milimeters) of the proximal forearm dorsal (both left and right)	10 minutes
skin thickness (in milimeters) of the proximal forearm ventral (both left and right)	10 minutes
skin thickness (in milimeters) of the deltoid region (both left and right)	10 minutes

Secondary

Measure	Time frame
Body Mass Index	at the moment of entering the study
Age	at the moment of entering the study
sex	at the moment of entering the study

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026