Magnetic Resonance Imaging to Assess Changes in Meniscus Vascularity

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02363140

Acronym

MOVE

Enrollment

Registered

2015-02-13

Start date

2012-06-30

Completion date

Unknown

Last updated

2016-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meniscus Tears

Keywords

Musculoskeletal System

Brief summary

The menisci in the knee joint are important for normal functioning of the knee. Meniscus tears are amongst the commonest of injuries to the knee. The pattern and blood supply of the meniscus tears determines the treatment plan and outcome. The surgeon identifies the blood supply to the meniscus tear area during the arthroscopy(key hole operation) and decides the treatment option ie repair versus partial meniscectomy. This study aims to identify any changes that occur in the meniscus blood supply. The following are the main aims of the 'MOVE'study- 1. Use of non-invasive methods ie MRImaging to assess meniscus vascularity to preoperatively plan treatment and advice patient on recovery. 2. The study would assess changes in meniscus blood supply depending on age of the patient. 3. The study aims to assess the alteration in meniscus blood supply following an arthroscopic(key hole) meniscal repair operation.

Interventions

OTHERWill undergo a single MRI assessment with intravenous dye

OTHERpre and post surgery MRI scan

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Inclusion criteria for Group I,II 1. Patients should be aged 18-20 years or 35-45years 2. Asymptomatic knee for past 6 months. 3. Painless flexion-extension movements at knee joint. Inclusion criteria for Group III 1. Patients should be aged 75 or older 2. Knee X-ray showing no more than Kellgren-Lawrence grade II osteoarthrtis 3. No clinical suspicion of meniscus tear 4. Painless flexion-extension movements at knee joint. Inclusion criteria for Group IV 1\. Patients should have presented with clinical signs to suggest meniscus tear indicating potential need for surgical meniscus repair.

Exclusion criteria

1. Proven Polyarthritis / Polyarthralgia secondary to Rheumatoid arthritis, Gout, Lupus, Ankylosing Spondylosis, Psoriatic arthritis 2. Any previous surgical procedure(open or arthroscopic) involving the knee joint.(baring the current meniscus repair in Group IV participants) 3. Patients unable to give informed consent. 4. Patients with contraindication for MR Imaging - Metal implants, prosthetic heart valves, pacemakers, metal foreign bodies, VP shunts, pregnancy, cochlear implant, metal clips in the brain, Patients with static tremor i.e. Parkinson's disease. 5. Patients with contraindications for contrast agent - Renal impairment, Previous allergic reaction.

Design outcomes

Primary

Measure	Time frame
Primary outcome is to assess meniscus vascularity in-vivo by use of MR imaging technique.	6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026