Metabolic Changes as a Diagnostic Indicator for Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02362776

Enrollment

426

Registered

2015-02-13

Start date

2009-10-31

Completion date

2012-07-31

Last updated

2015-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Lung Cancer

Keywords

NMR spectroscopy, metabolic changes, blood plasma, biomarker, cancer

Brief summary

This study aims to determine whether metabolic changes occur in blood plasma of cancer patients, and whether these changes can be used as a biomarker to detect cancer. These analyses will be done by means of nuclear magnetic resonance (NMR) spectroscopy.

Interventions

OTHERVenous blood sample

Collection of a venous blood sample to investigate metabolic changes in blood

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Diagnosis of breast or lung cancer (new lesion)

Exclusion criteria

* Not fasted for at least 6 hours * Plasma glucose concentration ≥ 200 mg/dl * Intake of medication at the day of investigation * History/treatment of cancer in the previous 5 years

Design outcomes

Primary

Measure	Time frame	Description
Metabolic phenotype of cancer	day 1	Significant metabolic changes in blood between cancer patients & control subjects

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 15, 2026