Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02362581

Enrollment

Registered

2015-02-13

Start date

2012-12-31

Completion date

2014-01-31

Last updated

2015-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia A, Prophylaxis

Keywords

Prophylaxis treatment, On demand treatment, Severe hemophilia A, Moderate hemophilia A

Brief summary

Comparison of prophylaxis and on-demand treatment in children with moderate to severe hemophilia A. This study determines to compare the efficacy of prophylaxis and on-demand treatment in moderate to severe hemophilia A children in King Chulalongkorn Memorial Hospital, Bangkok, Thailand

Interventions

OTHERprophylaxis treatment, on demand treatment

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

6 Months to 18 Years

Healthy volunteers

Inclusion criteria

* Age between 6 months to 18 years * Diagnosis severe and moderate hemophilia A

Exclusion criteria

* platelet \< 100,000/mm3 * No factor VIII inhibitor

Design outcomes

Primary

Measure	Time frame
Number of bleeding episodes require treatment	one year
number of school days lost	one year
Number of admission days	one year

Secondary

Measure	Time frame
Joint scores	one year
Quality of life score	one year
Amount of Facter VIII concentration used	one year

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026