The Comparison of Incidence and Risk Factors of Postoperative Delirium in Elderly Patients After Lower Extremity Surgery

Cukurova University Faculty of Medicine

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02360982

Enrollment

120

Registered

2015-02-11

Start date

2012-03-31

Completion date

2013-04-30

Last updated

2015-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Keywords

Delirium, regional anesthesia, general anesthesia

Brief summary

The aim of this study is to compare the risk factors and the incidence of delirium following orthopedic surgery under the general or regional anesthesia in elderly patients.

Detailed description

One hundred twenty elderly patients aged ≥65 years scheduled for total hip or knee arthroplasty and femur fracture surgery were enrolled into the study. Patients were allocated into two groups to receive regional anesthesia (group R, n=50) or general anesthesia (group G, n=70). Hemodynamic and blood parameters, potential risk factors of delirium including age, sex, duration of surgery, the type of anesthesia, coexisting disease, smoking and amount of drug used delirium tests (CAM and DRS-R-98), hospital stay and costs were recorded for all patients.

Interventions

BEHAVIORALpropofol and esmeron(rokuronyum)

All patients were evaluated at postoperative 24th and 72th hours with laboratory tests including hemoglobin, sodium, potassium, BUN, creatinine, total protein, albumin and glucose values in blood samples and delirium tests (CAM and DRS-R-98).

BEHAVIORALmarcaine and fentanyl

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologists physical status I-III, * 120 patients aged ≥65 years scheduled for total hip or knee arthroplasty and femur fracture surgery

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
the presence of postoperative delirium as defined by CAM criteria.	one year

Secondary

Measure	Time frame
severity of delirium rated with the DRS-R-9	one year
length of hospital stay and costs.	one year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026