Cancer, Cognition
Conditions
Keywords
Cognitive Dysfunction, Cancer Survivorship
Brief summary
At Cedars-Sinai Medical Center, we have developed a novel curriculum for a 6-week psycho-educationally-based, cognitive behavioral program to help patients with subjective cognitive complaints after cancer treatment, titled Emerging from the Haze™ (Haze). Each series meets once a week for 2 hours for 6 weeks. The leading neuropsychologist covers material such as guided relaxation, behavioral strategies for automatic/negative thoughts, compensatory strategies for attention and memory, executive functioning, pacing, and balance. Each Haze series will be electronically delivered in a live format to our satellite site, The University of Kansas.
Interventions
OTHEREmerging from the Haze
A 6 week psycho-educational class
Sponsors
University of Kansas
University of Pittsburgh
Cedars-Sinai Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Completed treatment for stage 1-3 breast cancer at least two months but not more than 24 months prior to enrollment. * Having received chemotherapy with or without radiation therapy * Female, Age ≥18 years. * FACT-Cog score less than 59 on the Perceived Cognitive Impairment subscale * Eligible after 2 months of completing all their active cancer treatment with the exception of long-term hormonal treatments or trastuzumab. * Subjective complaint of cognitive concerns at time of enrollment * Must be able to understand and communicate proficiently in English * Ability to understand and the willingness to sign a written informed consent. * Agree to complete study surveys
Exclusion criteria
* Patients who have significant personality disorders or unstable psychiatric disorders (including active major depression, substance abuse, psychosis or bipolar disorder) as assessed by the interviewing clinician * Patients with known brain metastases, history of brain metastases or radiation to the brain. * Patients with a history of stroke or other pre-existing neurological condition that may contribute to cognitive dysfunction. * Non-English speakers * Receiving treatment for another malignancy other than breast cancer * Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, chronic anemia, uncontrolled hypothyroidism, symptomatic congestive heart failure, unstable angina pectoris, uncontrolled cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| quantify the impact of Emerging from the Haze on breast cancer survivors' self-report of cognitive changes, based on change of the FACT-Cog- perceived cognitive impairment score from baseline to the end of the Haze series compared to the control group. | 6 weeks |
Countries
United States
Outcome results
None listed