Hemorrhage
Conditions
Keywords
Bleeding, Heart Surgery, Reoperation
Brief summary
Bleeding after redo cardiac surgery is a common, unresolved and consequences-heavy event as per present day. Tisseel (Baxter inc) sprayed on the already hemostased mediastinum jut before closing seems a promising technique to radically diminish bleeding. This study aims to verify this efficacy volume in chest drains) and possibly the consensual blood transfusion lessening.
Interventions
PROCEDURESpray Fibrin Sealant
Baxter Tisseel (Fibrin Sealant) is sprayed in the mediastinum at the end of the operation afetr routine chest hemostasis protocol has been completed, right before closing the chest.
PROCEDURETraditional Hemostasis and chest Closure Routine
Routine chest hemostasis and closure protocol (gauzes and inspection till satisfactory according to the surgeon)
Sponsors
Cardiochirurgia E.H.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients undergoing any kind of redo cardiac surgery with ati least one previous sternotomy
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bleeding (Amount of blood (ml) collected in chest drainage) | first 24 hours after surgery | Amount of blood (ml) collected in chest drainage in the first 24 hours after operation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Allogeneic blood Sparing (Amount of Allogeneic Blood units (number) transfused in the first 4 days after surgery) | 4 days after surgery | Amount of Allogeneic Blood units (number) transfused in the first 4 days after surgery |
Countries
Italy
Outcome results
None listed