Analysis of the Glutathione Cycle in Children With Rett Syndrome

EPITRA-14-001: Analysis of the Glutathione Cycle in Children With Rett Syndrome

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02360436

Enrollment

Registered

2015-02-10

Start date

2015-03-31

Completion date

2015-09-30

Last updated

2022-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rett Syndrome

Keywords

Rett, MeCP2, Glutathione, Cysteine, ROS

Brief summary

Analyis of the Glutathione Cycle in Children with Rett Syndrome

Detailed description

To analyze the levels of glutathione and relevant glutathione metabolites in children with Rett syndrome in an effort to better understand disease pathology and biochemistry.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

2 Years to 10 Years

Healthy volunteers

Inclusion criteria

* Age between 2 and 10, inclusive * Genetically-confirmed diagnosis of Rett syndrome with MeCP2 mutation * No change in dietary supplements in three months prior to the initial blood draw * No participation in interventional pharmaceutical clinical trials in prior 12 months

Exclusion criteria

* None other than meeting Inclusion criteria

Design outcomes

Primary

Measure	Time frame
Analysis of changes in levels of glutathione and relevant glutathione metabolites in children with Rett syndrome from baseline to the end of month 6	6 months

Countries

United States

Outcome results