Population Research of Sublingual Microcirculation Data of Healthy Volunteers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02359682

Enrollment

Registered

2015-02-10

Start date

2014-10-31

Completion date

2015-07-31

Last updated

2015-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

This study will enrolled 90 healthy volunteers. The sublingual microcirculation will be examined by sidestreamdark-field videomicroscopy (MicroScan;Microvision Medical, Amsterdam, The Netherlands). Five video sequences (20 s) was obtained from different sublingual sites, and digitally stored the images with code numbers that did not reflect volunteers' information for later offline analysis by automated analysis software (AVA 3.0; Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands).

Interventions

OTHERNo intervention

No Intervention

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

20 Years to 79 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy volunteers aged from 20 to 79 years old * BMI ranged from 18.5 to 27 kg/m2

Exclusion criteria

* Systolic blood pressure \> 140 mm Hg, diastolic blood pressure \> 95 mm Hg, or systolic blood pressure \< 90 mm Hg at enrollment * Body temperature \> 37.5 ℃ or \< 35.5 ℃ at enrollment * had been diagnose with any one of the following diseases * hypertension * diabetes mellitus * peripheral arterial occlusive disease * coronary arterial disease * liver cirrhosis * chronic kidney disease * stroke * anemia * asthma * chronic bronchitis * any metabolic diseases * any hematologic disease * uncured cancer * chronic uncontrolled infection * other disease may limit daily activities * non-native speakers

Design outcomes

Primary

Measure	Time frame	Description
Total small vessel density of sublingual small vessels	Once at enrollment	Total small vessel density will be measured by Microscan and analyzed by AVA 3.0 software.

Secondary

Measure	Time frame	Description
Perfused small vessel density of sublingual small vessels	Once at enrollment	Perfused small vessel density will be measured by Microscan and analyzed by AVA 3.0 software.

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026