Comparison of Pre-hospital and In-hospital Iv-tPA Stroke Treatment

Conditions

Ischemic Stroke

Keywords

stroke, thrombolysis, STEMO

Brief summary

This is a comparison of clinical outcomes between a pre-hospital and an in-hospital thrombolysis patient registry.

Christian H. Nolte, Martin Ebinger, Jan F. Scheitz, Alexander Kunz, Hebun Erdur et al. (17 authors)

Stroke2018-02-1930 citations

10.1161/strokeaha.117.019060

Functional outcomes of pre-hospital thrombolysis in a mobile stroke treatment unit compared with conventional care: an observational registry study.

Kunz A, Ebinger M, Geisler F, Rozanski M, Waldschmidt C, Weber JE, Wendt M, Winter B, Zieschang K, Fiebach JB, Villringer K, Erdur H, Scheitz JF, Tütüncü S, Bollweg K, Grittner U, Kaczmarek S, Endres M, Nolte CH, Audebert HJ.

2016-07-1690 citations

10.1016/s1474-4422(16)30129-6

Interventions

OTHERthrombolysis in a pre-hospital setting (STEMO concept)

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* Acute ischemic stroke diagnosis with thrombolytic treatment * Admission via EMS * Known premorbid status of need of assistance * NIHSS before treatment available * Time of onset (or last well seen) between 4:00am and 10:30pm

Exclusion criteria

* Unknown time of onset * In-hospital thrombolysis despite decision against treatment because of contraindications in STEMO

Design outcomes

Primary

Measure	Time frame	Description
modified Rankin Scale (mRS) score	three months after event	dichotomized mRS 0-1 and 2-6 in patients who lived at home without assistance prior to the index stroke.

Secondary

Measure	Time frame	Description
modified Rankin Scale (mRS) score	three months after event	dichotomized mRS 1-3 and 4-6

Countries

Germany

Outcome results

None listed