Is Phonophoresis Treatment Effective?

Is Phonophoresis Treatment Effective? Determination of Ibuprofen Levels by Microextraction and HPLC (High Liquid Pressure Chromatography) Method in the Tissues of the Patients With Knee Osteoarthritis?

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02358707

Enrollment

Registered

2015-02-09

Start date

2014-05-31

Completion date

2015-05-31

Last updated

2015-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Knee

Keywords

ibuprofen phonophoresis, High performance liquid chromatography

Brief summary

The specimens from patients as knee osteoarthritis diagnosed who was applied ibuprofen phonophoresis will be analyzed.

Interventions

OTHERIbuprofen phonophoresis

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* having diagnosed as osteoarthritis

Exclusion criteria

* surgery at knee * trauma at knee

Design outcomes

Primary

Measure	Time frame	Description
level of ibuprofen in bone by Microextraction and HPLC (High Liquid Pressure Chromatography)	1 year	Effectiveness and safety
level of ibuprofen in synovial membrana by Microextraction and HPLC (High Liquid Pressure Chromatography)	1 year	Effectiveness and safety
level of ibuprofen in synovial fluid by Microextraction and HPLC (High Liquid Pressure Chromatography)	1 year	Effectiveness and safety

Secondary

Measure	Time frame	Description
Visual Analog Scale (VAS)	1 year	VAS score after phonophoresis treatment

Countries

Turkey (Türkiye)

Contacts

Primary ContactBayram Kelle

bayramkelle@yahoo.com9003223386060-3161

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026