Tricuspid (Valve); Deformity
Conditions
Keywords
Cardiovascular Diseases, Heart Valve Diseases, Mitral Valve Annuloplasty, Tricuspid Valve Insufficiency
Brief summary
The purpose of this study is to evaluate the impact of isolated mitral valve annuloplasty on the geometry and the function of the tricuspid valve complex.
Detailed description
The proposed pathogenesis of functional tricuspid regurgitation (TR) in mitral valve disease seems incomplete. Because both atrioventricular valves are closely connected to each other by means of the cardiac fibrous skeleton, the geometry of the tricuspid valve is likely to be distorted after ring-annuloplasty of the mitral valve. This could lead to the development of functional TR, or to an increase in TR severity. To test this hypothesis, a prospective study will be started in patients undergoing isolated mitral valve annuloplasty.
Interventions
PROCEDUREMitral Valve Annuloplasty
Mitral valve annuloplasty by a rigid mitral ring, a semi-rigid ring, or a fully flexible band, at the surgeon's discretion
Sponsors
Universitaire Ziekenhuizen KU Leuven
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all patients 18 years of age or older undergoing minimally invasive, isolated mitral valve annuloplasty
Exclusion criteria
* concomitant tricuspid valve surgery * atrial fibrillation at the moment of surgery * poor echocardiographic windows
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative geometric changes in tricuspid valve annulus (TA) | day 0 | Measurement of changes in 3D descriptors of the TA (e.g. changes from baseline in the TA area of the best-fit plane in cm\^2, and changes from baseline in the height of each TA point to the TA best-fit plane in mm) |
Outcome results
None listed