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Acute Coronary Disease (ACS)- Strain

Analysis of Myocardial Deformation in Patients With Acute Coronary Disease

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02357641
Acronym
ACS-Strain
Enrollment
300
Registered
2015-02-06
Start date
2013-11-30
Completion date
2015-01-31
Last updated
2015-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac and Non Cardiac Thoracal Disorder

Keywords

acute coronary disease, echographic strain analysis, cut off

Brief summary

Examination of probable distinction between cardiac or non- cardiac thoracal disorder via echocardiographic myocardial strain analysis

Detailed description

Patients with cardiac disorder have to undergo time- consuming and expensive examinations such as laboratory of cardiac biomarkers or ischemic diagnostic. To save time and money in this observational registry the probable distinction between cardiac and non- cardiac disorder in patients with vague thoracal disorder and the probability for coronary artery disease (determined via Grace Score) is examined via echographic myocardial strain analysis in 300 patients retrospectively to establish a cut off value corresponding to acute coronary disease also to prevent coronary angiography. Therefore patients undergo echography routinely with consecutive evaluation of systolic, diastolic and strain analysis to elevate exact statements with reference to deformation of the myocard and its velocity. Several study have shown that these strain parameters (circumferential and radial strain) enable vitality and ischemic diagnosis and therefore could be eligible for this purpose.

Interventions

OTHERretrospective echographic myocardial strain analysis refering to acute coronary syndrome

retrospective evaluation for cut off value of circumferential and radial echographic strain parameters corresponding to acute coronary disease

Sponsors

RWTH Aachen University
Lead SponsorOTHER

Study design

Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* thoracal cardiac or non cardiac disorder * signed informed consent

Exclusion criteria

* glomerular filtration rate (GFR) \< 60 ml/min * angina pectoris * acute myocardial infarction within 3 months prior inclusion * pregnancy

Design outcomes

Primary

MeasureTime frame
Determination of cut off value of circumferential and radial myocardial echographic strain data corresponding to acute coronary disease1 year

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026