Mortality Reduction in Septic Shock by Plasma Adsorption

Reduccion de la Mortalidad Mediante Plasma-Adsorción en Shock séptico (ROMPA)

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02357433

Acronym

ROMPA

Enrollment

Registered

2015-02-06

Start date

2015-02-28

Completion date

2018-06-30

Last updated

2018-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Shock

Brief summary

The study objective is to clarify whether the application of high doses CPFA (Coupled Plasma-Filtration Adsorption) in addition to the current clinical practice is able to reduce hospital mortality in septic shock patients in intensive care unit (ICU).

Interventions

DEVICEHigh Doses CPFA

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* all patients admitted to the ICU in septic shock * all patients that develop septic shock while in the ICU

Exclusion criteria

* Age less than 18 years * Pregnancy * Estimated life expectancy (due to comorbidities) less than 90 days * Presence of relative or absolute contraindications to CPFA * Absence of informed consen

Design outcomes

Primary

Measure	Time frame
Hospital mortality	28 days

Secondary

Measure	Time frame	Description
time resolution of septic shock	within the first 28 days	normalization of lactate, and the decrease in vasoactive drugs

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026