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Driving Ability in Patients With CMT 1A

Driving Ability in Patients With CMT 1A

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02357355
Enrollment
32
Registered
2015-02-06
Start date
2014-11-01
Completion date
2016-07-01
Last updated
2017-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CMT 1A

Brief summary

Charcot Marie Tooth 1A (CMT 1A) is a common inherited disorder of the nerves in the body. The disease can result in difficulties with strength and balance as well as in foot deformities such as high arches, hammer toes, and tight ankles. Because of these difficulties, the disease may affect driving, especially because driving requires quick responses at times such as slamming on the brakes or turning the steering wheel quickly. The following study determines driving performance in individuals who have CMT 1A.

Detailed description

Individuals with CMT 1A will drive in a driving simulator, which involves a car located in a room in the University of Iowa Hospitals and Clinics (UIHC). Individuals will drive in the car as if they are driving in real life and the whole experience is like playing a car video game with a big animated screen. The driving results will be compared to similar aged patients who don't have CMT 1A and have also taken the driving test. If patients with CMT 1A do have driving difficulties compared to those who do not have CMT 1A, the results of the study will try to help patients with CMT1A drive better by ultimately creating devices that might help them use the steering wheel or brake pedal in a safer way.

Interventions

DEVICEUIHC Driving Simulator

This is a driving simulator located in the basement of the hospital. A car will be facing a large video screen of a driving simulation.

Sponsors

Jerath U Nivedita
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Have CMT 1A * Have a valid driver's license

Exclusion criteria

* History of other types of neuropathy (other than CMT 1A) * History of blindness, seizures, or stroke, dementia/cognitive dysfunction

Design outcomes

Primary

MeasureTime frame
Driving Error Rate1 year

Secondary

MeasureTime frame
Deceleration speed1 year
Time to braking1 year
Time to apply steering maneuvers1 year

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026