Stroke Patients
Conditions
Keywords
TST, TMS, Stroke patients, EMG
Brief summary
TST (Triple stimulation technique) helps to better quantify the proportion of motor units activated by transcranial magnetic stimulation. The abnormal amplitude registered by TST is proportional to the intensity of conduction disorders. The evaluation of these disorders is more precise with this technique than with the slowing of the central conduction time (CCT). The investigators propose to use this technique in CNS pathologies where this disorder is significant and essential, like multiple sclerosis and stroke.
Interventions
PROCEDURETriple stimulation technique
Evoked motor potentials obtained by magnetic transcranial stimulation are usually used, in standard practice, to evaluate the corticospinal tract. This procedure combines two techniques: the magnetic stimulation and the electroneuromyography. It is based on the double collision principle between the descending central stimulation (magnetic) and the ascending peripheric stimulation, hereby suppressing the issue of desynchronisation of evoked motor potentials. The Triple stimulation technique allows a better quantification of the proportion of motor units activated by the transcranial stimulation.
Sponsors
Brugmann University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* stroke patients with hemiparesia
Exclusion criteria
* pace maker * epilepsia * metallic neurosurgical implants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amplitude of the motor evoked potentials | during the TST (30 min) |
| Surface of the motor evoked potentials | during the TST (30 min) |
| Amplitude ratio of the TST | during the TST (30 min) |
| Surface ratio of the TST | during the TST (30 min) |
| TMS threshold | during TST (30 min) |
Countries
Belgium
Outcome results
None listed