Tinnitus
Conditions
Keywords
Q10, ubiquinol
Brief summary
The study is a randomised double-blinded trial. A group of 40 tinnitus patients with a naturally low Q10 level will be selected out of a preselected group of 160 screened out of a pre-existed database or patients which visited the ENT-consultation. The 40 patients with the lowest level will be asked to take 2 months Q10 (n=20) or the placebo (n=20). To evaluate the effect on hearing and tinnitus characteristic; audiometric test, tinnitus analysis and auditory evoked responses will be used as outcome measurements.
Interventions
DIETARY_SUPPLEMENTQ10
DIETARY_SUPPLEMENTplacebo
Sponsors
University Hospital, Antwerp
Study design
Allocation
RANDOMIZED
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* chronic non-pulsatile tinnitus \> 3 months * tinnitus has a clear otological cause * age \> 18 years
Exclusion criteria
* pulsatile tinnitus * persons who take already Q10 * pregnancy * cervical tinnitus * holocranial tinnitus * depression * mental of neurological disorders * history of chemotherapy * middle ear diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tinnitus Functional Index | 2 months |
Secondary
| Measure | Time frame |
|---|---|
| Tinnitus Analysis _ loudness matches | 2 months |
| Tinnitus Analysis_Minimal masking level | 2 months |
| Audiometric tresholds test | 2 months |
| Hospital Anxiety and Depression Scale | 2 months |
| Hyperacusis Questionnaire | 2 months |
| Visual Analogue Scale of loudness | 2 months |
Countries
Belgium
Outcome results
None listed