Coronary Heart Disease
Conditions
Keywords
Heart Rate, Percutaneous coronary intervention, outcome
Brief summary
The trial is a single centre, retrospective cohort, non-interventional study to be conducted in the department of cardiology, Chinese PLA General Hospital, Beijing, China. To evaluate the link between mean perioperative clinical heart rate and short-term composite outcomes during PCI among local CHD patients.
Detailed description
The study requires those data including subjects aged from 20 to 80 year-old, diagnosed as coronary heart disease with records on mean clinical heart rate during PCI from 2009.1 to 2014.5 in the database from the department of cardiology, Chinese PLA General Hospital, Beijing. All 15,000 subjects' related data from the database will be collected.Once selected, 15,000 patients in the retrospective cohort will be divided into 4 groups according to their mean clinical resting heart rate during PCI. Group 1 will be defined as subjects' mean clinical resting heart rate ≤70 BPM, which will be set as baseline. Group 2 will be defined as subjects' mean clinical resting heart rate between 71 to 80 BPM. Group 3 will be defined as subjects' mean clinical resting heart rate between 81 to 90 BPM. Group 4 will be defined as subjects' mean clinical resting heart rate \>90 BPM. The primary endpoint is to determine the link between the mean perioperative heart rate and short-term outcomes during PCI among local CHD patients.
Interventions
None listed
Sponsors
Dandan Li
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients consecutive enrolled in Chinese PLA General Hospital from January 2009 to May 2014 * Diagnosed as coronary heart disease with records on mean clinical heart rate during PCI .
Exclusion criteria
* Inferior wall myocardial infarction (MI) history or/and acute inferior wall MI patients; * Dead within 3 days after admit into wards; * LVEF\<30%; * Install a permanent pacemaker patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with composite events including CVD mortality, fatal/non-fatal MI, non-fatal sudden cardiac arrest, fatal/non-fatal stroke and malignant arrhythmia | During PCI |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mean perioperative clinical heart rate | During PCI | The primary efficacy endpoint is proportion of patients with composite events including CVD mortality, fatal/non-fatal MI, non-fatal sudden cardiac arrest, fatal/non-fatal stroke and malignant arrhythmia. |
| Clinical resting heart rate and heart rate variability | During PCI | — |
Contacts
Primary ContactDandan Li, M.D.
Outcome results
None listed