Gait, cOgnitiOn & Decline (GOOD)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02350270

Enrollment

2800

Registered

2015-01-29

Start date

2015-01-31

Completion date

2015-12-31

Last updated

2015-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy, Mild Cognitive Impairment, Mild Dementia, Moderate Dementia

Keywords

cognitively healthy individuals

Brief summary

The main objective of the GOOD initiative was to determine which spatio-temporal gait parameters and/or combination(s) of spatio-temporal gait parameters best differentiate between cognitively healthy individuals (CHI), patients with mild cognitive impairment (MCI) and those with mild and moderate dementia.

Detailed description

Gait disorders are frequent in individuals with cognitive disorders. However, the profile of spatio-temporal gait parameters in the different cognitive status in aging (from normal cognition to dementia) has been poorly studied. Determining this profile associated with the severity of cognitive disorders may be helpful to understand the complex interplay between gait and cognitive disorders and, thus, may have important implication for the diagnosis process of patients with and without dementia. For instance, defining a motor phenotype of the severity of cognitive disorders by using quantitative gait measurements could be used to improve the prediction and the diagnosis of dementia. The investigators hypothesized that, compared to CHI, people with MCI and mild dementia could be characterized by specific phenotypes of spatio-temporal gait parameters measured with the GAITRite® system, and that these profiles could be explained by declines in domain-specific cognitive performance.

Interventions

OTHERgait and cognitive testing

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Being 60 years old and older * Ability to answer questions

Exclusion criteria

* Opposition to the use of information collected for research purposes

Design outcomes

Primary

Measure	Time frame	Description
Spatio-temporal gait parameters	This outcome is assessed at inclusion	Spatio-temporal gait parameters were measured at steady state walking using GAITRite®-system.

Secondary

Measure	Time frame	Description
Clinical assessment	This outcome is assessed at inclusion	This outcome was assessed by a questionnaire.
Cognitive status	This outcome is assessed at inclusion	Cognitive status was assessed by cognitive testing.

Countries

France

Contacts

Primary ContactOlivier Beauchet, MD, PhD

olbeauchet@chu-angers.fr++33 2 41 35 57 38

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026