Osseointegrated Dental Implantation
Conditions
Brief summary
The main objective of this clinical trial study is to consider the effect of Platelet-Rich-Factor (PRF) on implant stability and marginal bone resorption around dental implants.
Detailed description
Dental implants were placed in 30 subjects who have 1 or 2 missing teeth in both side of posterior mandible. Implants with a length of 11.5 and a diameter of 4.5 mm will be inserted in both sides. In one side PRF will be instilled after surface treatment with PRF before implant placement, while no PRF was added in other side to serve as control group. All implants will be followed with stability measurement by means of resonance frequency analysis at baseline, and every two weeks up to 3 months. Bone height was measured on medial & distal side on standardized IOPA x-rays.
Interventions
BIOLOGICALPRF
implant stability was measured by RFA and implant resorption was measured by IOPA after surface treatment by PRF
Sponsors
Reza Tabrizi
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* patients who have 1 or 2 missing teeth in both side of posterior mandible * adequate bone quantity and quality at the implant site * the implant sites with at least 3 months of healing after extraction, * patients well motivated for implant therapy and maintaining good oral hygiene * the implant sites with width and length to installation of an implant of 4.5 mm x 11.5 mm. * Patients who gave written informed consent
Exclusion criteria
* • medically compromised or patients taking any immunosuppressive drugs which may complicate the treatment outcome * infection around the implant site * history of bruxism/parafunctional habits * patients with history of any bleeding disorder or on anti-coagulant therapy. * pregnant patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| implant loss | 6 months | During the osseointegration, if the implant lose his stability and if the patient have pain, the implant will be removed and the implant will be considered lost |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ISQ analysis | 3 months | Since the implant installation, the implant stability will be measure with the Osstell, that will return a number between 0 and 100. This represents the Implant Stability Quotient (ISQ). The difference between the ISQ results will be the secondary outcome measure |
| bone height (mm) | 6 months | Since the implant insertion , bone height was measured in mesial and distal side on standardized IOPA x-ray |
Countries
Iran
Contacts
Primary ContactReza Tabrizi, DMD
Outcome results
None listed