Pressure Ulcer
Conditions
Brief summary
The purpose of this study is to investigate if wound dressings are capable in reducing the effects of shear- force at the skin. With our own shear- force model we are able to apply 19 Newton shear- force combined with 9 newton pressure at the skin of the non- dominant forearm. After half an hour we measure IL-1alpha/ total protein- ratio, cutaneous blood flow (Laser doppler, Moor LDI) and the erythema index (DSMIIColormeter) which occurs as an effect of shear- force application at the skin. Then, we apply 19 Newton shear- force combined with 9 Newton pressure at the dominant fore-arm but this time we put a wound dressing between the skin and shear- force model. After half an hour we measure the IL-1alpha/total protein-ratio, cutaneous blood flow and the erythema index. This research consists of three research day, each day we are going to investigate a different wound dressing
Interventions
OTHERshear- force
19 Newton shear- force and 3,9 kPa pressure for half an hour
Sponsors
Maastricht University Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* healhty volunteer * age 18- 30 * BMI 20- 30
Exclusion criteria
* Trauma fore-arms * Diabetes mellitus type I or type II * The use of NSAID's in the last 7 days * Vascular diseases * Muscular dystrophy * Malignancy * Participant is unable to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cutaneous blood flow, erythema index, IL-1alpha/Total protein ratio | Directly after intevention |
Outcome results
None listed